Endocrine Abstracts

Objective: Vitamin D is an immune-modulator that may play a role in thyroid related autoimmunity. But the relation between Vitamin D and Graves’ disease (GD) is not well defined yet. The aim of this study was to investigate the association of 25-hydroxy-vitamin D (25[OH]D) levels and TSH receptor antibody (TRab) levels in GD.Design: A total of 429 GD patients were analyzed retrospectively. 122 of 429 patients had vitamin D levels were enrolled in th...

Background: Osteoporosis is a common problem in postmenoausal women. There is limited data about the physiological importance of endogenous testosterone on bone mineral density (BMD) in older women is poorly understood.Aim: The aim of this study was to evaluate association of endogeneous testosterone with BMD and BMI.Materials-methods: This cross-sectional study included 64 patients (45–85 year) postmenopausal women; their dem...

Background: Diabetes is very common disorder. Many studies have shown that patients with diabetes mellitus have incresing trombotic complications both arterial and venous trombosis. Bad control diabetes increases risk of trombosis. Recent reports have shown that shortened APTTs and increased fibrinogen indicate procoagulan situations. In this study, we aimed to evaluate whether chronic hyperglisemia or bad control diabetes causes trombosis which is reflected by shortened APTTs...

Objective: Radioiodine (RAI), surgical and anti-thyroid drug therapy are the main options to treat Graves’ disease (GD). The aim of this study was to investigate theurapeutic options, their efficacy and adverse reactions of prophilthiouracil (PTU) and methimazole (MMI).Design: A total of 650 patients with GD were evaluated retrospectively. Treatments, adverse reactions, clinical and laboratory results were recorded. After 18 months of primary medica...

Introduction: Pregnant women with known hypothyroidism must have monthly follow up with thyroid function tests. Appropriate L-thyroxin replacement dose can be given due to trimester specific thyroid stimulating hormone (TSH) levels. We will discuss about a hyperthyroid pregnant woman who was taking L-thyroxin replacement before and during the first trimester of pregnancy for hypothyroidism.Case: A 24-year old woman came to o...

Background: Hypogonadism is related to additional endocrine abnormalities. Thyroid abnormalities may be common in hypogonadism patients, although this association is not clear.Objective: In this study, we examined the incidence of thyroid disorders in hypogonadisms.Methods: A case–control study of 68 hypogonadal patients and 74 age-matched healthy controls from the general population was conducted. Thyroid function, thyroid vo...

Introduction: Metastatic pituitary tumors are seen rarely and it is hard to differentiate them from the benign lesions of the gland. We have reported a case, with a known maxillary sinus tumor, detected to have a pituitary lesion coincidentally on PET-CT.Case: 45 years old male patient with a known history of relapsed maxillary sinus tumor has been referred to our clinics because of the pituitary lesion detected to have increased FDG involvement on PET-C...

Introduction: Premature ovarian failure is cessation of ovarian function before the expected age, which is usually accepted to be 40. Autoimmune diseases are a frequently seen group of disorders causing premature ovarian failure. In this study, we aimed to evaluate the frequency of autoimmune thyroiditis in patients with premature ovarian failure.Material and method: Patients who admitted to our thyroid out patient clinic were included to our study. The ...

Background: Acromegaly is a relatively uncommon disorder (40–68 cases per million population) caused by oversecretion of growth hormone by a tumor of the pituitary gland. Excessive growth hormone (GH) and insulin-like growth factor (IGF) I concentrations cause gradual changes in facial and acral appearances as well as in many internal tissues.Medhods: Medical records of patients with acromegaly seen between 2000 and 2008 at our hospital were reviewe...

When follicular thyroid carcinoma (FTC) is diagnosed, 25% of the patients extrathyroidal invasion, 5–10% lymphatic metastasis and 10–20% distant metastasis are determined. The most common site of distant metastases of FTC is the lung, followed by the bone. The incidence of skull metastasis of FTC is about 2.5–5.8%. Skull metastasis of FTC was located in the skull base and occipital area.Case: A 60-year-old man admitted at 2006. He was oper...